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Foreskin retracted under anaesthetic with the phimotic ring or stenosis constricting the shaft of the penis and creating a "waist". Common signs and symptoms include painful urination, penis discharge, and sores or blisters on the penis or in the genital area. Hormone imbalances, especially testosterone deficiency, have been linked to erectile dysfunction.
Penile cancer — which might begin as a blister on the foreskin, head or shaft of the penis and then become a wartlike growth that discharges watery pus — also is a rare possibility. Foreskin retraction may happen immediately after birth, or it may take several years. Are circumcised penises cleaner?
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Stroke, spinal cord and back injuries, multiple sclerosis, and dementia can affect the transfer of nerve impulses from the brain to the penis, causing erectile dysfunction. In particular, foreskins obtained from newborns have been found to be useful in the manufacturing of more human skin.